Strange sound
The noise means there is too much of a gap between the valves and
rocker arms, what you hear is the slack being taken up before the
rocker arm contacts the valve. The main problems with this condition is
that it hurts your engine performance and gas mileage. Since there's
too much of a gap, that means the valves are not opening as much as
they should and the heads are not taking in as much air/fuel or venting
as much exhaust gasses as they should. Over an extended period of time,
several months, this could lead to other problems.
If this is a fairly new condition, the trip should be fine. When you're
accelerating and you start hearing the noise, back off the accelerator
a little, don't push it too hard for too long.
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