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Scientists propose six-drug pill could cut heart attacks, stroke

The Associated Press
Friday, June 27, 2003

One pill combining six medications could prevent more
than 80 percent of heart attacks and strokes if heart
patients, most diabetics and everyone older than 55 took
it, British scientists said.

However, the American Heart Association cautioned that
such a pill might be dangerous for healthy people and not
strong enough for those with heart trouble. It could also
lull some people into persisting with life-threatening
habits.

The concept, outlined Thursday on the Web site of the
British Medical Journal, is the brainchild of two
University of London doctors, Nicholas Wald and Malcolm
Law.

Called the "polypill," it would contain aspirin, a statin
drug to lower cholesterol and folic acid to reduce levels
of homocysteine, an amino acid that promotes hardening of
the arteries. Three types of blood pressure drugs -- an
ACE inhibitor, a beta-blocker and a diuretic -- would be
included at half the standard dose -- enough, the doctors
say, to lower blood pressure without causing as many side
effects as when the drugs are used individually at higher
doses.

The scientists based their finding on evidence from more
than 750 existing studies involving 400,000 participants
taking heart medications.

Read the complete news at:
http://www.startribune.com/stories/1556/3958960.html

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