13th April 19:18
NEWSFLASH!!! BIOMARKER A SIGNIFICANT PREDICTOR OF OUTCOME PCa
hi folks - this just in - the study was presented oct. 21 at the annual
meeting of the american society for the****utic radiology and oncology
in salt lake city.
the presence of a biomarker called Ki-67 may be a significant predictor
of outcome for prostate cancer patients treated with both hormones and
radiation, say researchers at Fox Chase Cancer Center in Philadelphia.
When a tumor cell tests positive for Ki-67, which is a proliferation
antigen, that means the tumor is actively growing.
Previous smaller studies by the Fox Chase scientists found the greater
the proportion of prostate tumor cells with Ki-67, the more aggressive
the cancer. those previous studies involved small patient numbers and
didn't conclusively establish the usefulness of the Ki-67 biomarker
"our(new) study conclusively shows that Ki-67 was the most significant
determinant of distant metastasis and death in prostate cancer
patients." Dr. alan Pollack, chairman of radiation oncology at Fox
chase, says in a prepared statement.
"the relationship of Ki-67 to patient outcome is a continuous function ,
wherein the higher the per cent of Ki-67, the greater the risk of
adverse result,. in addition, Ki-67, along the PSA, Gleason score and
stage, appears to be valuable in determining whether high-risk patents
may be spared long-term androgen deprivation," pollack says.
knowledge is power - growing old is mandatory - growing wise is optional