hepautomagic

(not a large study group, I know, but interesting)

Hepatology Research
Volume 26, Issue 4 , August 2003, Pages 327-329

Copyright © 2003 Elsevier B.V. All rights reserved.
Preliminary note
Branched-chain amino acids supplements in the late evening decrease
the frequency of muscle cramps with advanced hepatic cirrhosis

Katsumi Sakoa, Yasushi Imamura, , b, Hiroto Nishimataa, Kenji
Taharab, Osamu Kubozonob and Hirohito Tsubouchic

a Nanpuh Hospital, Nanpuh, Japan
b Kagoshima Kouseiren Hospital, 22-25 Tenpozan-cho, Kagoshima 890-
0061, Japan
c Department of Internal Medicine, Miyazaki Medical College,
Miyazaki, Japan

Received 14 May 2002; revised 10 February 2003; accepted 12 March
2003. ; Available online 24 April 2003.

Abstract
Eight outpatients with advanced hepatic cirrhosis were tested over 3
months for branched-chain amino acids (BCAA) supplements in the late
evening. Serum albumin level (2.8±0.3 vs. 3.1±0.2 g/dl, P<0.002),
serum cholin esterase activity (54±13 vs. 67±17 IU/l, P<0.02), and
plasma Fischer's ratio (1.3±0.9 vs. 1.4±0.9, P<0.005) increased over
the 3 months. The frequency of muscle cramps decreased (7.4±2.0 vs.
0.3±0.5 times/week, P<0.0001) dramatically. These data suggest that
BCAA supplements in the late evening are of benefit to malnourished
patients with hepatic cirrhosis. Relief of muscle cramping is an
important outcome of BCAA supplements in the late evening.

Author Keywords: Hepatic cirrhosis; Nocturnal supplementation;
Branched-chain amino acids


Corresponding author. Tel.: +81-99-252-2228; fax: +81-99-252-2736

anonymous

In article <ec181702.0309131240.64b3a80d@posting.google.com >

Yes Hamboner. Everybody knows you are abstract.

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