pureheart

Plast Reconstr Surg. 2003 Jun;111(7):2295-306.

Biodurability of retrieved silicone gel breast implants.

Brandon HJ, Jerina KL, Wolf CJ, Young VL.

This study ****yzed the shells of single-lumen silicone gel breast
implants within the general context of device durability in vivo. The
investigation included the major types of gel-filled implants that
were manufactured in the United States in a 30-year period. The
implants ****yzed were Cronin seamed (two explants and one control),
Silastic 0 and Silastic I (18 explants and seven controls), and
Silastic II (22 explants and 43 controls). The biodurability of the
explants was investigated with measurements of the mechanical and
chemical properties of the various types of silicone gel control and
explanted shells, with implantation times ranging from 3 months to 32
years. The shell properties measured for the controls and explants
included the stress-strain relationships, tensile strength,
elongation, tear resistance, moduli, cross-link density, and amount of
extractable material in the shell. In addition, the mechanical
properties of shells that had been extracted with hexane were ****yzed
for both explants and control implants. The silicone gel explants
investigated in this study included some of the oldest explants of the
various major types that have been tested to date. For assessment of
long-term implantation effects, the data obtained in this study were
combined with all known data from other institutions on the various
major types of gel implants. The study also addressed the failure
mechanisms associated with silicone gel breast implants. The results
of the study demonstrated that silicone gel implants have remained
intact for 32 years in vivo and that degradation of the shell
mechanical and chemical properties is not a primary mechanism for
silicone gel breast implant failure.

PMID: 12794472 [
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12794472&dopt=Abstract

kathi

I also posted: (I am trying to get my hands on the full article)

J Long Term Eff Med Implants. 2003;13(1):49-61
"New Giudelines - Protocol for retrieval and ****ysis of breast implants"
Brandon HJ, Young VL, Watson ME, Wolf CJ, Jerina KL.

Center for Implant Retrieval and ****ysis, Washington University,
St. Louis, Missouri 63130, USA. hjb@mecf.wustl.edu

http://groups.google.com/groups?dq=&start=25&hl=en&lr=&ie=UTF-8&group=alt.support.breast-implant&selm=c2c88781.0307121056.784209bd%40posting.google.com

kathi

He has been very involved in this issue for years ...

Here's a post from last year regarding the HLA work that seemed
promising that he was doing.

~~~~~~~~~~~~

From: ilena@san.rr.com (Ilena Rose)
Newsgroups: alt.support.breast-implant
Subject: Some Women With Breast Implants May Be Genetically
Predisposed to Illness
Date: Sat, 04 Aug 2001 01:12:38 GMT

QUESTIONS:

Why isn't this being studied further?

Why aren't women being tested PRE-implants now to see if they may have
a
genetic pre-disposition?

This says: "Young and his co-workers are now trying to find out what
is
triggering the production of autoantibodies."

Really? Where are the updates?

Where are the follow ups?
[It was 3 years ago when our Linda Dintino posted this.]