Cytomel vs. Synthroid (triiodothyronine thyroid)
As others have said, the gland makes primarily T4, tetraiodothyronine,
which gets coverted to T3, triiodothyronine by an enzyme elsewhere in
the body. T3 is four to eight times as active as T4. Most
endocrinologists do, as others said, prescribe T4. A lot of GPs and
rheumatologists use Armour thyroid, which once was dessicated beef
thyroid and was once the only replacement available. I think it is now
a mixture of synthetic or purified T3 and T4. It is possible that a
subset of people have normal T4 and low peripheral enzymes, so are
functionally hypothyroid despite normal blood levels of T4.
Endocrinologists often measure free T4, free T3, and almost always
measure thyroid stimulatig hormone (TSH). TSH is the pituitary hormone
that drives thyroid activity. The usual assumption is that if the
pituitary is happy (that is, if TSH levels are normal) all is well no
matter what the T4 level and if TSH is abnormal, there is a problem
somewhere, no matter what the T4 level.
|