davidbeckham1111

"In 2001 apomorphine was licensed under the trade names Uprima and
Ixense, and was the only other oral treatment for erectile
dysfunction. Two new rival drugs both work in a similar way to Viagra.
Cialis was launched on 4 February 2003 by Eli Lilly. GlaxoSmithKline's
drug Levitra is also due to be launch in 2003.

How does apomorphine work?

Unlike Viagra, which acts on the penis, apomorphine has its effect in
the brain. Individual nerve cells in the brain and nervous system
communicate with one another using chemical messengers called
neurotransmitters. Apomorphine mimics the action of one of the brain's
main neurotransmitters, dopamine, and is thought to act primarily on
an area of the brain called the hypothalamus. Areas of the
hypothalamus are thought to control the more reflexive side of our
***ual response including ******l blood flow in women and erection in
men. By mimicking the action of dopamine in the hypothalamus,
apomorphine strengthens the signals the brain sends to the penis to
cause an erection."

Source: http://www.bbc.co.uk/science/horizon/2003/***chemqa.shtml

Given that dystonia is a MISFIRING of the neurotransmitters surely
taking drugs for erectile dysfunction may make dystonia WORSE?

And if so then probably also a risk for Parkinsons.

And if so shouldn't there be a warning?

suz-q

David, I am glad that you posted this information... I found something
similar a few years ago in a diet medication that upped
norephrine..which would stimulate dopamine and spasms too,,, It might
help the beginnings of Parkinsons before they get on Levodopa.(Sinemet).

Sue

davidbeckham1111

So as the sales of Viagra-substitutes becomes mroe widespread is this
likely to lead to an incrase in cases of dystonia? What are the veiws
of the DMRF over this?

Also as many males with dystonia suffer from low self-esteem it is
likely that there will be a higher percentage of erectile dysfunction
(anxiety related) among dystonia (or similar diseases) sufferers than
those with no ailments. If so...then taking the viagra substitute will
exacerbate their dystonia.

Again - what are the views of the official bodies on this?