good results in unresectable pancreatic cancer patients to intraoperative radiotherapy (cancer tumor)
Radiat Med. 1998 May-Jun;16(3):195-200.
Response of unresectable pancreatic cancer to intraoperative radiotherapy.
Department of Radiology, Hirosaki University School of Medicine, Aomori,
Japan.
Eight patients with unresectable pancreatic cancer were treated by
intraoperative radiotherapy (IORT) with electron beams, and the tumor
responses were followed using serial CT scans. In five cases, external beam
irradiation with 10 MV X-rays was added. While there was no evident change
after 2-3 weeks, 6-8 weeks after IORT partial responses were noted in all
five examined cases. Furthermore, 12-16 weeks after IORT, three out of five
examined patients showed good tumor response with more than 75% regression.
Mean survival time was 8.0 +/- 2.7 months. Two patients who lived longer
than 1.5 years had shown excellent tumor responses. Serial CT scans in the
early period following IORT allowed accurate estimation of the tumor
response, which might predict some long-surviving cases.
|