ironjustice

<<snip>>
ac***ulation of non-heme iron and free radicals in the white matter
after head trauma.
<<snip>>

J Neurol Sci. 2007 Jul 30; [Epub ahead of print]
Low signal intensity and increased anisotropy on magnetic resonance
imaging in the white matter lesion after head trauma: Unrecognized
findings of diffuse axonal injury.Okanishi T, Saito Y, Fujii S,
Maegaki Y, Fukuda C, Tomita Y, Ohno K.
Division of Child Neurology, Institute of Neurological Sciences,
Faculty of Medicine, Tottori University, 36-1 Nishi-cho, Yonago
683-8504, Japan.

We report on a four-year-old girl with head trauma caused by a motor
vehicle accident. She presented with delirium, oculomotor palsy and
ptosis in her left eye, left hemiparesis, and pyramidal signs in all
extremities. Computed tomography on the day of admission showed
diffuse cerebral edema with right-sided predominance. Magnetic
resonance images on day 3 of admission showed lesions of diffuse
axonal injury and contusion in the corpus callosum and right occipital
and bilateral temporal lobes. There was a low-intensity lesion in the
white matter of the right hemisphere on T2-weighted images, fluid-
attenuated inversion recovery, T2()-weighted images, apparent
diffusion coefficient maps and diffusion-weighted images. This low-
intensity lesion disappeared by day 7, and a transient brain atrophy
in the right hemisphere appeared on day 28. The low signal intensity
in the cerebral white matter was apparently different from that
associated with contusion and typical diffuse axonal injury, and might
represent a late-onset ac***ulation of non-heme iron and free radicals
in the white matter after head trauma.

PMID: 17669430 [PubMed - as supplied by publisher]

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