james michael howard

Bull Exp Biol Med. 2006 May;141(5):571-3.Prolonged decrease in stress
reactivity caused by dehydroepiandrosterone sulfate.

Obut TA, Ovsyukova MV, Cherkasova OP.
Institute of Physiology, Siberian Division, Russian Academy of Medical
Sciences, Novosibirsk.

In male rats exposed to repeated stress, the decrease in stress reactivity
produced by subcutaneous injection of dehydroepiandrosterone sulfate
(recorded by the decrease in stress-induced concentrations of
corticosterone and adrenocorticotropic hormone in blood plasma) was
observed 1-6 days postinjection and involved central regulatory mechanisms.