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3rd July 10:09
External User
Posts: 1
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Hypertension can be caused by too many red blood cells.
Reduction of red blood cells controls this .. hypertension .. caused by erythrocytosis .. increased red blood cells. "therapeutic effect of phlebotomy in posttransplant hypertension associated with erythrocytosis." ------------------------------------------------------------------------------ http://tinyurl.com/2r5uqs Hypertension: Uncontrolled and Taking Over the World LONDON, UK -- August 16, 2007 -- The biggest problem for controlling hypertension (high blood pressure) is compliance with treatment, says an Editorial in this week's Cardiology Special Edition of The Lancet. The Editorial, which ties in with a Seminar on hypertension, says: "Despite very effective and cost-effective treatments, target blood pressure levels are very rarely reached, even in countries where cost of medication is not an issue. Many patients still believe that hypertension is a disease that can be cured, and stop or reduce medication when blood pressure levels fall." The risk of becoming hypertensive for a person in a developed country exceeds a "staggering" 90%, and the increasingly common combination and interaction of hypertension with obesity, diabetes and hyperlipidaemia, if left untreated for too long, leads to cardiovascular disease, stroke, renal failure and death. The disease burden of hypertension is expected to massively increase in the coming years. In 2000, the estimated number of adults living with high blood pressure was 972 million; this is expected to increase to 1·56 billion by 2025. The Editorial says: "Lifestyle factors, such as physical inactivity, a salt-rich diet with high processed and fatty foods, and alcohol and tobacco use, are at the heart of this increased disease burden, which is spreading at an alarming rate from developed countries to emerging economies, such as India and China." The Editorial concludes: "Physicians need to convey the message that hypertension is the first, and easily measurable, irreversible sign that many organs in the body are under attack. Perhaps this message will make people think more carefully about the consequences of an unhealthy lifestyle and give preventative measures a real chance." The Seminar, authored by Dr. Franz Messerli, Division of Cardiology, St Luke's-Roosevelt Hospital Center, Columbia University, New York and colleagues, takes a detailed look at hypertension, its underlying causes and associated risk factors. The authors state that neither beta-blockers nor thiazide diuretics should be used as first line therapy in uncomplicated hypertension. They conclude: "Most hypertensive patients need two or more drugs for blood-pressure control and concomitant statin treatment for risk factor reduction. Despite the availability of effective and safe antihypertensive drugs, hypertension and its concomitant risk factors remain uncontrolled in most patients." SOURCE: The Lancet ----------------------------------------------------------------------------------------------------- Clin Nephrol. 1993 Oct;40(4):241-3. Related Articles, Links Therapeutic efficiency of phlebotomy in posttransplant hypertension associated with erythrocytosis. Barenbrock M, Spieker C, Rahn KH, Zidek W. Medizinische Poliklinik, Westfalischen Wilhelms-Universitat, Munster, Germany. Hypertension is a major complication in kidney transplantation and contributes to the high cardiovascular mortality of renal transplanted recipients. The aim of the present study was to evaluate the therapeutic effect of phlebotomy on blood pressure in posttransplant hypertension associated with erythrocytosis. In 12 renal transplanted patients (7 male, 5 female, aged 29-52 years) with erythrocytosis (defined by hematocrit > 52% or hemoglobin > 170 g/l), a 24-hour-monitoring of blood-pressure and heart rate (SpaceLabs SL90207) was performed before, 2 and 6 weeks after phlebotomy. Patients with iron-deficiency and/or transplant rejection were excluded from the study. Ten of 12 patients were on antihypertensive treatment before phlebotomy. Phlebotomy (500 ml) was repeated three times on average within the first two weeks, until hematocrit decreased below 45%. The phlebotomy therapy lowered the hematocrit after two weeks from 54.8 +/- 2.8% to 44.3 +/- 4.2% and 43.0 +/- 5.6% after six weeks. Before phlebotomy, the blood pressure was systolic 153.2 +/- 15.1 mmHg and diastolic 95.2 +/- 9.5 mmHg. After repeated phlebotomy, there was a significant decrease of blood pressure to systolic 139.0 +/- 14.1 and diastolic 85.3 +/- 8.2 mmHg (p < 0.01). Without change of hematocrit and hemoglobin, there was no further change of blood pressure after six weeks (systolic 140.1 +/- 9.9 mmHg, diastolic 86.3 +/- 9.5 mmHg). The heart rate did not change significantly during the therapy. The antihypertensive treatment could be reduced in most of the patients. The present study demonstrates the therapeutic effect of phlebotomy in posttransplant hypertension associated with erythrocytosis.(ABSTRACT TRUNCATED AT 250 WORDS) Publication Types: Clinical Trial PMID: 8261683 [PubMed - indexed for MEDLINE] ---------------------------------------------------------------------------*----- Who loves ya. Tom Jesus Was A Vegetarian! http://jesuswasavegetarian.7h.com Man Is A Herbivore! http://tinyurl.com/a3cc3 DEAD PEOPLE WALKING http://tinyurl.com/zk9fk Who loves ya. Tom Jesus Was A Vegetarian! http://jesuswasavegetarian.7h.com Man Is A Herbivore! http://tinyurl.com/a3cc3 DEAD PEOPLE WALKING http://tinyurl.com/zk9fk |
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