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4
17th May 01:09
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In article<FUETgwBZ4zaAFwb4@xemu.demon.co.uk>, Dave Bird <dave.xemu.dele
teThe@nospam.demon.co.uk> writes: Apomorphine is useful for its dopaminergic effect against Parkinsonism and female sexual duysfunction, but its chief -- and dose limiting effect -- is that it makes you vomit. This is because there is too much peripheral dopamine. I expect the effect of peripheral dopamine is basically parasympathetic (feeding and sex) boosting, but too much of it produces too much salivation hence vomiting. If this dopamine is being made peripherally from the precursor "L-dopa" i.e. dopaminic acid by decarboxylation, would "Carbidopa" -- as given with L-Dopa for parkinsonism -- reduce the problem? -- "If I have seen further than other men, (0_ it is because I have been surrounded (o. | (o. (o. by pygmies." /\ //\ /\ /\ \/_ V_/_ \/_ \/_ |
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