Mkelley360 2008-09-13 15:52:30
What solvent dissolves the pill, oxycontin, into a liquid for safe
intravenous use? I have heard many different answers to this question
and do not think any of these solvents are safe for intravenous
injection. (ie. vinegar, alcohol ect…)
Computernewby 2008-09-13 15:52:30
I find many oxymorons in your question. First of all if you are going to
experiment illegally with this drug which is obviously what is going to
happen then there is no safe way to inject this drug. That is why it comes
as a tablet so that it can be swallowed whole without crushing, chewing,
snorting or injecting which can lead to overdose or death.
Oxycontin (oxycodone) comes in tablets, oral liquid and suppositories.
So to answer your question, there is no answer since it is a moot point.
Gregory poon 2008-09-13 15:52:47
Yet people will still try to “suspend” the tablets in something and inject
it … and end up in the ER with endocarditis. Or clogging up something
else and get an infarct. Just great.
Sendmyshithere 2008-09-13 15:52:49
The waxy polymer used in OxyContin’s and MS Contin’s require mixed
solvent systems, the best ones being 80-85% mineral spirits and 15-20%
toluene. These should be boiled with the crushed up pills. Then an
aqueous phase needs to be mixed into the solvent system. For MS
Contin’s it is best to convert the Morphine Sulphate into Morphine HCl
which is more soluble in water. Oxycodone is already the HCl so this
is not necessary.
After the mixture is allowed to seperate into an organic layer and an
aquous layer, the aqueous layer should be drawn off the bottom using
a syringe, leaving the organic layer in tact. More water should then
be added to the organic layer and the extraction should be repeated.
The excess water should then be evaporated or rotovaped until a
managable amount is left. The pH should then be adjusted to about 5.5
to 6.0, otherwise the shot will burn.
Note that this is not a simple procedure and should only be done with
proper lab setup. You do not want to use an open flame or a stove.
Also, make sure you remove the outer coating of the pills with water
and a Q tip.
Timbertea 2008-09-16 09:29:51
The solvent isn’t the issue, the issue is the particulate matter that is
going to be present when you crush this pill up. Make this a habit and
you’ll end up with nasty abcesses and destroyed veins if not worse. Not
that Oxycodone is all that kind to veins either.
But if you insist on injecting this, at least run it though a .2 micron
filter first to rid most of the particulate and just use normal sterile
saline solution. It’s still risky, but far less likely to destroy your
Patrick 2008-09-16 09:30:00
If oxycodone hydrochloride were meant for intravenous use then it would
be manufactured that way. For many reasons it is not. #1) there are many
other IV opiates that are more efficacious when given IV, #2) Oxycodone
Hcl as such is pretty damned acidic and if not buffered it is going to be
very nasty on the veins and cause damage if not maybe even a clot.
If you want to die of a pulmonary embolism, go ahead, not a fun way to
Patrick H. Mason M.S. OHST, EMT-I
Matt beckwith 2008-09-16 09:31:00
Lead with an insult. That’s a good tactic if you have nothing to say. Way to go.
Follow up the insult with a sentence with no subject and no verb. Now
your audience is totally confused. I presume that’s exactly where you wanted him, right?
Follow the sentence fragment with a run-on sentence. The reader is
reeling from the dizziness, totally in awe of your syntactical
brilliance. Furthermore, he’s waiting in breathless anticipation of
the “many oxymorons” you found, not one of which has yet been mentioned.
Now you switch gears entirely and state the obvious. The reader is now
wondering whether you’ve led him on by mentioning the oxymorons. But
at least he’s comforted by a sentence which is actually grammatically correct.
And here’s the coup de grace. You had nothing to say to begin with!
What a finish!
Matt beckwith 2008-09-16 09:31:01
Patrick, perhaps you failed to infer that the original poster is a drug
abuser and doesn’t have legal access to intravenous narcotics.
Not that all drug abusers do not have access to intravenous narcotics.
I once knew an IV dilaudid-using pharmacist, who needless to say had no
The Internet is such an interesting place, not least because it brings
together people who would normally have no opportunity to communicate.
I don’t think someone who is addicted to narcotics is going to let the
risk to his own life stop him from using an unsafe preparation. After
all, addicts are not in control of their actions by definition. The
drug is in charge, not the drug addict. That’s why they can’t quit
Patrick 2008-09-16 09:31:09
Patrick H. Mason M.S. OHST, EMT-I