Hi pete'
I'm working as information security consultant and I've never heard about
exploiting this configuration.
Even if junk mail sent to the user, most of the times is does not come back
again as a result of sending an "out of office" message,
I think that the probability to exploit this feature is low,
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Nir Valtman
http://blogs.microsoft.co.il/blogs/valtmanir/
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Do you think that information security is expansive? Try to ignore it