Ifmyfriendscou 2010-03-29 22:45:07
HOWEDY pat aka unsurreality aka mike dufort you anonymHOWES
miserable stinkin lyin animal an child an spHOWES abusin punk
thug coward active acute chronic long term incurable mental case,
HERE’S HOWE COME YOUR OWN DEAD DOG GOT DEAD, mikey:
“Warning: Sometimes The Corrections Will Seem
Quite Harsh And Cause You To Cringe. This Is
A Normal Reaction The First Few Times It Happens,
But You’ll Get Over It.” mike duforth,
author: “CourteHOWES Canine.”
“I have heard advice stating that you should pre-load
your dog for Bitter Apple for it to work as efficiently
as possible. What does this mean?
When you bring home the Bitter Apple for the first time,
spray one squirt directly into the dog’s mouth and walk
away. The dog won’t be too thrilled with this but just
ignore him and continue your normal behavior.”
–Mike Dufort
author of the zero selling book
“CourteHOWES Canines”
Canine Autoimmune Hemolytic Anemia
Mental stress as a risk factor for medical conditions
Introduction: There are various other conditions for
which stress is a risk factor. For general information
on stress, see also stress, complications of stress,
and stress as a symptom.
Auto-immune mediated anemia (AIMA) also called autoimmune
hemolytic anemia (AIHA) and immune mediated hemolytic anemia
(IMHA): antibodies formed against antigens in the red blood
cell membrane cause these cells to burst open. The resulting
anemia compromises the dog’s ability to provide sufficient
oxygen for cell function throughout the body.
Immune-mediated thrombocytopenia (ITP): a dangerously low
level of platelets – either due to an increase in antibody
and complement-mediated phagocytosis of platelets in the
spleen, bone marrow and liver, or decreased production due
to antibody and/or complement mediated phagocytosis of
platelet stem cells (megakaryocytes) in the bone marrow.
The low platelet levels lead to spontaneour bleeding,
often nose bleeds or petechiation (bleeding just under
the skin and mucous membranes) are seen. Blood in the
stool, urine or vomit is less common. (Often seen with
AIHA, SLE and RA.)
Owners may note the presence of blood in the urine or
stool. An increase in temperature may also be observed
in some dogs. A diagnosis of AIHA is made on the basis
of these clinical signs as well as a CBC. A Coomb’s
test should be performed to confirm the diagnosis.
A small percentage of dogs that have AIHA will test
negative on the Coomb’s test.
Most of the time, a specific cause for AIHA is unrecognized.
Many theories exist, but the ultimate answer is “We don’t know.”
Dr. Jean Dodds, a veterinarian studying immunology, states in
her article; “The Immune System and Disease Resistance” that
there are four main causative factors of autoimmune diseases.
Those factors are: Genetic predisposition; Hormonal influences;
Infections, especially of viruses and Stress.
Dr. Dodds also feels that the multivalent modified-live vaccines
overstimulate the immune system. There may be evidence to support
this theory because the Merck Veterinary Manual states: ” recently,
the most typical cases of AIHA in dogs have been marked by a
nonregenerative anemia. Some of these cases have occurred after
exposure to parvovirus or modified live parvovirus vaccine.”
Others blame environmental pollutants, or food preservatives
such as ethoxyquin, an antioxidant found in most dog foods.
There are still others who believe there is a link between AIHA
and some drugs. There is strong evidence for a genetic factor
in the development of AIHA. Although all breeds can be affected,
the Basenji, West Highland White terrier, English springer spaniel,
Alaskan malamute, poodle, and beagle breeds can be congentially
predisposed to this condition due to defects in enzymes (such as
pyruvate kinase). Females are affected with AIHA 3-4 times more
frequently then males.
—————
Autoimmune thyroiditis (hypothyroidism) is generally found with
the other autoimmune diseases or may occur by itself. Loss of
thyroid hormones is manifested early by behavioral changes –
aggression, hyperactivity, anxiety/fear, compulsive behaviors,
phobic behaviors; allergies and reduced resistance to bacterial,
viral, fungal and protozoal infection – often manifest as skin
and respiratory disorders. Seizure disorders are also often
related to low thyroid levels. As the disease progresses lethargy,
obesity, alopecia (loss of hair/poor haircoat especially on the
sides) and infertility are more common.
Hypoadrenocorticism (Addison’s disease): The adrenal gland
produces hormones which regulate the level of sodium and
potassium (mineralocorticoids) and mediate the body’s
response to physiologic and psychologic stress (corticosteroids).
The former are needed to maintain proper cell function, their
loss is seen as muscle weakness and eventually heart failure
as the heart’s muscle cells can no longer produce the nervous
impulses needed for the heart to contract. Gastrointestinal
function is also usually impaired, and weight loss is frequently
seen. Animals are less able to cope with mild, everyday occurences
and hide, refuse to eat and show other symptoms of stress.
SLE: Known as the great imitator can be hard to diagnose as it
can manifest as a disease of the skin/mucous membranes/nails,
kidney and/or joints as has already been described. SLE can
also affect the brain producing signs of cognitive dysfunction.
It is also hard to diagnose definitively as not all dogs with
SLE have postive ANA titers.
Cause of Addison’s Disease: Failure to produce adequate levels
of cortisol, or adrenal insufficiency, can occur for different
reasons. The problem may be due to a disorder of the adrenal
glands themselves (primary adrenal insufficiency) or to inadequate
secretion of ACTH by the pituitary gland (secondary adrenal
insufficiency).
Addison’s disease is a rare endocrine or hormonal disorder
that affects about 1 in 100,000 people. It occurs in all age
groups and afflicts men and women equally. The disease is
characterized by weight loss, muscle weakness, fatigue, low
blood pressure, and sometimes darkening of the skin in both
exposed and nonexposed parts of the body.
Addison’s disease occurs when the adrenal glands do not produce
enough of the hormone cortisol and in some cases, the hormone
aldosterone. For this reason, the disease is sometimes called
chronic adrenal insufficiency, or hypocortisolism. 1
Cushing’s syndrome is a disorder of the adrenal glands leading
to excess cortisol secretion. This means that there is too much
cortisol hormone in the blood. It can be caused by an adrenal
gland failure, or it can result from a pituitary tumor or other
tumor that secretes ACTH which in turn stimulates the adrenal
glands to over-produce cortisol.
Cushing’s syndrome information: Cushing’s syndrome is a hormonal
disorder caused by prolonged exposure of the body’s tissues to
high levels of the hormone cortisol. Sometimes called
“hypercortisolism,”
it is relatively rare and most commonly affects adults aged 20 to 50.
An estimated 10 to 15 of every million people are affected each year. 1
Prevalance of Cushing’s syndrome: it is relatively rare and most
commonly affects adults aged 20 to 50. Exposure to too much cortisol
can occur for different reasons such as long-term use of glucocorticoid
hormones to treat inflammatory illnesses; pituitary adenomas (benign
tumors of the pituitary glands) which secrete increased amounts of
adrenocorticotropic hormone (ACTH); ectopic ACTH syndrome (a condition
in which ACTH is produced by various types of potentially malignant
tumors that occur in different parts of the body); and adrenal tumors
(tumors of the adrenal glands). 2 Sometimes, an abnormality of the
adrenal glands, most often an adrenal tumor, causes Cushing’s syndrome.
Cause details for Cushing’s syndrome: Cushing’s syndrome occurs when
the body’s tissues are exposed to excessive levels of cortisol for
long periods of time. Many people suffer the symptoms of Cushing’s
syndrome because they take glucocorticoid hormones such as prednisone
for asthma, rheumatoid arthritis, lupus or other inflammatory diseases.
Others develop Cushing’s syndrome because of overproduction of cortisol
by the body. Normally, the production of cortisol follows a precise
chain
of events. First, the hypothalamus, a part of the brain which is about
the size of a small sugar cube, sends corticotropin releasing hormone
(CRH) to the pituitary gland. CRH causes the pituitary to secrete ACTH
(adrenocorticotropin), a hormone that stimulates the adrenal glands.
When the adrenals, which are located just above the kidneys, receive
the ACTH, they respond by releasing cortisol into the bloodstream.
Cortisol performs vital tasks in the body. It helps maintain blood
pressure and cardiovascular function, reduces the immune system’s
inflammatory response, balances the effects of insulin in breaking down
sugar for energy, and regulates the metabolism of proteins,
carbohydrates, and fats. One of cortisol’s most important jobs is to
help the body respond to stress. For this reason, women in their last 3
months of pregnancy and highly trained athletes normally have high
levels of the hormone. People suffering from depression, alcoholism,
malnutrition and panic disorders also have increased cortisol levels.
When the amount of cortisol in the blood is adequate, the hypothalamus
and pituitary release less CRH and ACTH. This ensures that the amount
of cortisol released by the adrenal glands is precisely balanced to
meet the body’s daily needs. However, if something goes wrong with the
adrenals or their regulating switches in the pituitary gland or the
hypothalamus, cortisol production can go awry. 1
http://www.wrongdiagnosis.com/a/ai/intro.htm
Autoimmune diseases information: Disease caused by a malfunctioning
immune system leading to self-attacks or self-stimulation of other body
cells.
Autoimmune diseases information: The word “auto” is the Greek word for
self. The immune system is a complicated network of cells and cell
components (called molecules) that normally work to defend the body and
eliminate infections caused by bacteria, viruses, and other invading
microbes. If a person has an autoimmune disease, the immune system
mistakenly attacks self, targeting the cells, tissues, and organs of a
person’s own body. A collection of immune system cells and molecules at
a target site is broadly referred to as inflammation. 1
Conditions list: The list of conditions in the Autoimmune diseases
group includes:
* Possibly Autoimmune Diseases
* Type 1 diabetes
* rheumatoid arthritis
* Autoimmune thyroid diseases
* Graves Disease
* Hashimoto’s Thyroiditis
* Systemic Lupus Erythematosus
* Multiple Sclerosis
* Crohn’s disease
* Psoriasis
* Psoriatic Arthritis
* Sympathetic ophthalmitis
* Autoimmune neuropathies
* Autoimmune oophoritis
* Autoimmune orchitis
* Autoimmune Lymphoproliferative Syndrome
* Antiphospholipid syndrome
* Sjogren’s Syndrome
* Rheumatoid arthritis
* Scleroderma
* Lupus
* Addison’s Disease
* Polyendocrine deficiency syndrome
* Polyendocrine deficiency syndrome type 1
* Polyendocrine deficiency syndrome type 2
* Guillain-Barre Syndrome
* Immune Thrombocytopenic Purpura
* Pernicious anemia
* Myasthenia Gravis
* Primary biliary cirrhosis
* Mixed connective tissue disease
* Primary Glomerulonephritis
* Vitiligo
* Autoimmune uveitis
* Autoimmune Hemolytic Anemia
* Autoimmune Thrombocytopenia
* Celiac Disease
* Dermatitis herpetiformis
* Autoimmune Hepatitis
* Pemphigus
* Pemphigus Vulgaris
* Pemphigus Foliaceus
* Bullous Pemphigoid
* Autoimmune Myocarditis
* Autoimmune Vasculitis
* Autoimmune eye diseases
* Alopecia Areata
* Autoimmune Atherosclerosis
* Behcet’s Disease
* Autoimmune Myelopathy
* Autoimmune Hemophilia
* Autoimmune Interstitial Cystitis
* Autoimmune Diabetes Insipidus
* Autoimmune Endometriosis
* Relapsing Polychondritis
* Ankylosing Spondylitis
* Autoimmune Urticaria
* Paraneoplastic Autoimmune Syndromes
* Dermatomyositis
* Miller Fisher Syndrome
* IgA nephropathy
* Goodpasture syndrome
* Herpes gestationis
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